Noninvasive Clinical Monitor for Early Detection of Shock


<p>To test a new instrument for the diagnosis and monitoring of shock</p>

Anticipated Impact: 

<p>Improved outcomes in trauma patients and formation of a start-up company to commercialize the new shock monitor</p>


Shock is a life-threatening medical condition that results in insufficient oxygen reaching body tissues. Early and definitive diagnosis of shock is difficult using current methods. As a result, many cases are missed or not picked up until the critical later stages when organ failure and death may occur. The investigators have developed a novel noninvasive clinical monitor that they believe will fundamentally improve the early detection and continuous monitoring of shock. A proof-of-concept study will be performed on trauma patients upon admission to the emergency department and within the first hours of resuscitation in the intensive care unit. The investigators hope to demonstrate that their new monitor can identify the severity of shock and serve as a sensitive indicator of the adequacy of resuscitation. The commercialization plan for the shock monitor includes the formation of a new start-up company.

See also:


Shock Early Detection

Grant Update

Principal Investigator:
Kenneth Schenkman
Grantee Organization:
University of Washington
Grant Title:
Noninvasive clinical monitor for early detection of shock
Grant Cohort and Year:
2009 Winter Commercialization (03)
Grant Period:
12/07/2009 - 12/06/2011 (Completed)
Grant Amount:
We have successfully enrolled an initial set of patients into our study who have suffered traumatic injury or who suffer from sepsis. Preliminary analysis of data from these patients shows that their muscle oxygenation is abnormally low upon arrival in the Emergency Department, compared with a group of healthy control subjects. With this initial set of patients we can see a stratification of shock severity based on our muscle oxygen measurement. These preliminary results are encouraging that measurement of muscle oxygenation may be a very useful tool to help identify patients at risk for shock, regardless of cause, and may be very helpful in monitoring their response to treatment.

Impact in Washington

Location of LSDF Grantee
Locations of Collaborations/Areas of Impact

Legislative Districts:
11, 34, 36, 37, 43, 46

Health Impacts

Shock Early Detection