Washington Phenotyped Biospecimen Resource

Focus: 

To develop a resource to provide high-quality, information-rich biological samples to researchers and startup companies statewide

Anticipated Impact: 

Improved diagnostics and treatments for major health conditions

Abstract: 

Progress in basic and translational research on human disease depends increasingly on access to samples of fluids (e.g., blood) and tissue ("biospecimens") from large and diverse populations. Obtaining such specimens can be complicated and time-consuming for scientists and their research organizations. The Washington Phenotyped Biospecimen Resource (WPBR) will overcome these obstacles by creating an infrastructure to make specimens more readily available. This infrastructure will also make the process simpler and more efficient for those patients who wish to contribute to medical research. All specimens will be “clinically annotated,” meaning that they will be linked to biologically relevant data on the donors. The WPBR will: (1) make existing specimens available to biomedical investigators at non-profit and for-profit organizations throughout Washington, (2) facilitate collection and widespread distribution of new specimens specifically for research, (3) allow specimens from a single individual to be obtained at multiple time points, and (4) facilitate identification of consenting patients for inclusion in clinical trials. This grant will support development of the information system, initial steps towards sample handling, and other needed capital-intensive infrastructure, allowing the resource to become financially self-sufficient within three to four years.

Collaborating organizations: Microsoft, Pacific Northwest National Laboratory, PATH

See also:

Biospecimen Resource

Grant Update

Principal Investigator:
John Slattery
Grantee Organization:
University of Washington
Grant Title:
Washington Phenotyped Biospecimen Resource
Grant Cohort and Year:
2010 Program Grant (02)
Grant Period:
01/01/2012 - 12/31/2014 (Completed)
Grant Amount:
$1,784,747
On the strong foundation established by LSDF grants to the Consortium Biospecimen Resource at Fred Hutchinson Cancer Research Center and the Washington Phenotyped Biospecimen Resource at the University of Washington, our two institutions have established Northwest BioTrust (NWBT). NWBT fulfills the original intent of the LSDF awards, to make available well-characterized biospecimens for the advancement of life sciences research in the State of Washington. We have built and tested the systems for obtaining and recording patient consent, capturing the specimen and data specifications from researchers and delivering blood and tissue specimens in accordance with researcher needs. A five-year business plan has been set in motion which will lead to a self-sufficient resource designed to meet the needs of a broad research community. We expect that the results of the research enabled by the services of NWBT will have lasting and positive benefits for the citizens of Washington.

Impact in Washington

Location of LSDF Grantee
Locations of Collaborations/Areas of Impact
Seattle
Redmond
Richland

Legislative Districts:
8, 11, 34, 36, 37, 43, 46, 48

Health Impacts

Biospecimen Resource