Atrial Fibrillation Screening

Focus: 

To assess the clinical effectiveness of a small and inexpensive device as a screening tool for atrial fibrillation, a known cause of stroke

Anticipated Impact: 

Lowered risk of stroke through treatment of individuals with asymptomatic atrial fibrillation

Abstract: 

Stroke is the third most common cause of death in Washington state and in the United States overall. In Washington, stroke is involved in over 25,000 hospitalizations per year and over 6% of total hospital charges. Asymptomatic atrial fibrillation is a known cause of stroke. Mortality for atrial fibrillation-related stroke is twice that of non-atrial fibrillation-related stroke. If a patient is known to have atrial fibrillation, treatment with medications is available that can reduce the risk of stroke by more than 80%. Atrial fibrillation can be difficult and expensive to detect with current technologies. Novel technologies developed at the University of Washington (UW) allow inexpensive, convenient, and accurate screening of patients at risk, in order to initiate treatment before a potentially devastating or fatal stroke. This project will use the newly developed UW techniques to identify subjects in King County who are at risk for asymptomatic atrial fibrillation. At the end of the project, the investigators will have pilot data on the incidence of asymptomatic atrial fibrillation as it relates to risk factors and ethnicity, as well as valuable initial experience in using novel screening hardware on human subjects.

Collaborating organization: Cardiac Insight, Inc.

See also:   

Atrial Fibrillation Screening

Grant Update

Principal Investigator:
David Linker
Grantee Organization:
University of Washington
Grant Title:
Screening for Atrial Fibrillation, a Cause of Preventable Strokes
Grant Cohort and Year:
2011 First Round Commercialization (03)
Grant Period:
03/01/2012 - 02/29/2016 (Completed)
Grant Amount:
$150,000
Our study has used data collected from over 4,200 volunteers in King County to develop a method to predict a person's risk of atrial fibrillation, a common heart rhythm disturbance. The method does not require any tests, unlike previous methods, yet it is more accurate. This means that doctors will be able to more accurately determine who should undergo more detailed screening. Since January 2, 2014, we have been placing a newly developed Band-Aid sized heart monitor on subjects selected from this same group of volunteers, without known atrial fibrillation. It will record their heart rhythm for a week while they go about their normal activities, to see if they have atrial fibrillation which has not been previously diagnosed. We are also recruiting subjects without known atrial fibrillation to wear the monitor from the Cardiology clinic at the University of Washington Medical Center, and have recruited a total of 134 subjects so far. Analysis of the recorded data is ongoing.

Impact in Washington

Location of LSDF Grantee
Locations of Collaborations/Areas of Impact
Seattle

Legislative Districts:
11, 34, 36, 37, 43, 46

Health Impacts

Atrial Fibrillation Screening