Next Generation Articulating Surfaces for Load-bearing Implants

Focus: 

To test a safer artificial joint material

Anticipated Impact: 

Artificial joints that will be safer and still durable

Abstract: 

Load-bearing implants such as artificial hips and knees need to be very durable because of the wear and pressure placed on them. Alloys used in metal-on-metal implants have the longest life while retaining strength, but slowly release toxic metal ions into the body. Expensive and risky operations to replace implants have been necessary when metal implants are recalled. Alternatives such as ceramic and polyethylene have significant disadvantages of either durability or strength. A novel combination of ceramic and metal alloy, which is expected to retain the durability of metal while reducing its toxicity, will be tested in two animal models for wear and durability. The generation of a biomimetic lubricating film, which is expected to be more easily generated with the hybrid material, will also be tested. 

Collaborating organizations: Biomet, West Bengal University of Animal & Fishery Sciences

Artificial Joints

Grant Update

Principal Investigator:
Amit Bandyopadhyay
Grantee Organization:
Washington State University
Grant Title:
Next Generation Articulating Surfaces for Load-bearing Implants
Grant Cohort and Year:
2014 Proof of Concept (03)
Grant Period:
03/16/2014 - 03/15/2016 (Completed)
Grant Amount:
$250,000
As a part of our LSDF program, we have processed calcium phosphate (CaP) reinforced CoCrMo composites using laser based 3D Printing technology, Laser Engineered Net Shaping (LENS). We have tested our samples for wear degradation. Our results indicate that addition of CaP increased wear resistance and minimized metal ion release in CoCrMo samples. We have also tested these samples for in vivo biocompatibility assessment using rat and rabbit distal femur model. In vivo analysis indicate that these samples are non-toxic and biocompatible.

Impact in Washington

Location of LSDF Grantee
Locations of Collaborations/Areas of Impact
Pullman

Legislative Districts:
9

Health Impacts

Artificial Joints