Transforming the paradigm of sudden cardiac arrest resuscitation: Patient-specific treatment through innovative technology

Focus: 

To improve the rate of resuscitation following sudden cardiac arrest with individualized, patient-specific resuscitation guidance

Anticipated Impact: 

More effective resuscitation following sudden cardiac arrest, leading to fewer deaths and decreased disability

Abstract: 

Out-of-hospital heart attacks, or sudden cardiac arrests (SCA), are a major public health challenge and account for 10 percent of deaths in the United States. Public health researchers from the University of Washington and the Seattle & King County Department of Public Health have improved the rate of successful resuscitation from a typical 20% to a world-leading 60%. Further improvements to the resuscitation rate will be achieved through development of an individualized approach, “Smart Resuscitation.” Working with leading defibrillator manufacturer and commercialization partner Philips, algorithms that measure the CPR rate, identify the heart rhythm during continuous CPR, and gauge the heart’s physiologic status will be combined into a prototype defibrillator that will inform patient-specific treatment during SCA resuscitation. LSDF funds will be matched with an equal total from King County EMS and Philips Healthcare (which has its primary research and development program in emergency care and resuscitation in Bothell, Washington). This grant builds on work funded through a previous LSDF grant.

Collaborating organizations: Philips Healthcare, Seattle & King County Department of Public Health

Cardiopulmonary Resuscitation

Grant Update

Principal Investigator:
Thomas Rea
Grantee Organization:
University of Washington
Grant Title:
Transforming the paradigm of sudden cardiac arrest resuscitation: Patient-specific treatment through innovative technology
Grant Cohort and Year:
2015 Matching (05)
Grant Period:
05/01/2015 - 04/30/2018 (Active)
Grant Amount:
$350,000
During this phase of the Smart Resuscitation project, the team has developed the data infrastructure to test, refine, and validate algorithms designed to measure CPR in real-time, identify the ECG rhythm during CPR, and generate a vitality assessment of the specific ECG rhythm. We continue to generate the data infrastructure, which requires a detailed second-by-second review to generate a “gold-standard” from in order to develop and validate the Smart Resuscitation algorithms. The SMART Resuscitation team has successfully validated a real-time CPR detection algorithm. We have made substantial progress on algorithms designed to achieve rhythm identification and assess the heart’s vitality. We are currently working toward peer-review presentation and publication as a means to demonstrate the robustness and relevance of these novel advances. We are also investigating the potential implications for care based on implementation of these algorithms. We are pleased by the ongoing and planned participation of Philips and King County EMS to advance the SMART Resuscitation project.

Impact in Washington

Location of LSDF Grantee
Locations of Collaborations/Areas of Impact
Seattle
Bothell

Legislative Districts:
1, 11, 34, 36, 37, 43, 46

Health Impacts

Cardiopulmonary Resuscitation